The Endocannabinoid System

The Endocannabinoid System?

Your body naturally has CB1, and CB2 receptors, located throughout the human body studies show that CBD modifies the CB1 and CB2 receptors, which helps these receptors fight off inflammation.

Human CBD Receptor Chart

Endocannabinoid System

CBD, CBG, CBN, and THC fit like a lock and key into existing receptors. These receptors are part of an Endocannabinoid system, which impacts psychological processes affecting pain, modulation, and appetite, plus anti-inflammatory effects and other immune system responses. This system comprises two types of receptors, CB1 and CB2, which serve distinct functions in the well-being of animals and human health.

Cannabinoid Receptors

The cannabinoid receptors are G protein-coupled receptors that are activated by endocannabinoids or exogenous agonists such as tetrahydrocannabinol. CBD does not directly fit. CB1 or CB2 receptors but has powerful indirect effects that are still being studied.

The Endocannabiniod System

The Endocannabinoids system and its CB1 and CBD2 receptors are present throughout the body, including the brain, organs, connective tissues, glands, and immune system.

Although the cannabinoid system performs different functions in each tissue, its aim remains the same: to maintain homeostasis or a balanced internal environment despite changes in the external environment.

Endocannabinoids are a crucial link between the body’s systems, facilitating communication and coordination between different cell types.

When there is an injury, cannabinoids can reduce the release of activators and sensitizers from the damaged tissue, stabilizing the nerve cell to prevent excessive firing and calming nearby immune cells to prevent the release of pro-inflammatory substances. Three different mechanisms carry out these actions on three different cell types to minimize pain and damage resulting from the injury.

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